The 37th Texas Legislature established the Los Fresnos Independent School District in 1921.

The Texas Legislature House Journal of the House of Representatives of the Texas Legislature, page 1097, passed the following House Bill on March 12, 1921.

H.B. No. 554: "An Act creating the Los Fresnos Independent School District in Cameron county, Texas, and defining its boundaries; providing for the election of a board of trustees therefor; providing for the selection of a secretary, treasurer, assessor and collector of taxes and all other necessary officers and committees and prescribing their qualifications; investing said district with all the rights, powers, privileges and duties of a town or village incorporated under the general laws of the State for free school purposes only, and declaring an emergency."
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